ATG7 抗体
Quick Overview for ATG7 抗体 (ABIN4901029)
抗原
See all ATG7 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ATG7 is a protein encoded by the ATG7 gene which is approximately 77,9 kDa. ATG7 is localised to the cytoplasm. It is involved in the autophagy pathway, class I MHC mediated antigen processing and presentation, the HIV life cycle and oncogenic MAPK signalling. It is an E1-like activating enzyme that is essential for autophagy and transport from the cytoplasm to the vacuole. It is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. ATG7 is expressed in the nervous system, liver, kidney, intestine and lung. STJ98914 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous ATG7 protein.
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特异性
- The antibody detects endogenous ATG7 protein.
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产品特性
- Mouse Monoclonal to ATG7.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Recombinant peptide derived from ATG7.
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应用备注
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WB 1:500-2000
ELISA 1:10000-20000 -
说明
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Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- ATG7 (ATG7 Autophagy Related 7 (ATG7))
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别名
- ATG7
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分子量
- 78kDa
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基因ID
- 10533
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UniProt
- O95352
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途径
- Response to Water Deprivation, Autophagy
抗原
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