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CD81 抗体

This 小鼠 单克隆 antibody specifically detects CD81 in FACS, WB, IP, ICC, Func 和 IHC (p). It exhibits reactivity toward 人, 兔 和 Cat.
产品编号 ABIN4888503
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD81 抗体 (ABIN4888503)

抗原

See all CD81 抗体
CD81

适用

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人, 兔, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD81 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

M38
  • 原理

    Anti-Hu CD81 Purified Low Endotoxin

    特异性

    The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

    交叉反应 (详细)

    Human, Feline (Cat), Rabbit

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    内毒素水平

    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

    免疫原

    MOLT-4 (human T-ALL cell line)

    亚型

    IgG1
  • 应用备注

    Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
    Flow cytometry: recommended dilution: 1 μg/mL.
    Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    CD81

    别名

    CD81

    背景

    CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

    基因ID

    975

    UniProt

    P60033

    途径

    Inositol Metabolic Process, Hepatitis C
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