8-OHDG 抗体
(3 references)Our Local Distributor
北京 101111
Quick Overview for 8-OHDG 抗体 (ABIN488679)
抗原
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-8-Hydroxyguanosine | DNA/RNA oxidative damage (clone 15A3)
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特异性
- Recognizes markers of oxidative damage to DNA (8-hydroxy-2?-deoxyguanosine,8-hydroxyguanine and 8-hydroxyguanosine).
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交叉反应 （详细）
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Recognizes markers of oxidative damage to DNA (8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine)
Not reactive in: No confirmed exceptions from predicted reactivity are currently known -
纯化方法
- Protein G purified
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免疫原
- 8-hydroxy-guanosine-BSA and - casein conjugates
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亚型
- IgG2a
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anti-8-Hydroxyguanosine (8-OHDG) antibody
8-OHDG ELISA, IHC 宿主: 小鼠 Monoclonal N45-1 unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG ELISA, IHC, IP, FACS, FM 宿主: 小鼠 Monoclonal 15A3 unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG IHC (p), EIA, IHC (fro) 宿主: 小鼠 Monoclonal 15A3 unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG ELISA, IHC, WB 宿主: 小鼠 Monoclonal 15A3 unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG IHC (p), EIA, IF 宿主: 小鼠 Monoclonal N45-1 unconjugated
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应用备注
- The optimal working dilution should be determined by the investigator
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说明
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protocol for immunostaining using this antibody can be found here
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Total IgG fraction. Protein G purified.
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注意事项
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
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储存条件
- -20 °C
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储存方法
- Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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: "Cavitation during the protein misfolding cyclic amplification (PMCA) method--The trigger for de novo prion generation?" in: Biochemical and biophysical research communications, Vol. 461, Issue 3, pp. 494-500, (2015) (PubMed).
: "Application of BY-2 cell model in evaluating an effect of newly prepared potential calcium channel blockers." in: Pakistan journal of pharmaceutical sciences, Vol. 28, Issue 4, pp. 1281-93, (2015) (PubMed).
: "8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures." in: International archives of occupational and environmental health, Vol. 80, Issue 1, pp. 1-15, (2006) (PubMed).
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: "Cavitation during the protein misfolding cyclic amplification (PMCA) method--The trigger for de novo prion generation?" in: Biochemical and biophysical research communications, Vol. 461, Issue 3, pp. 494-500, (2015) (PubMed).
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- 8-OHDG (8-Hydroxyguanosine (8-OHDG))
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别名
- 8-Hydroxyguanosine
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物质类
- Chemical
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背景
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Background: Oxidative derivate of guanosine is called 8-Hydroxyguanosine (8OHdG) and is used as a popular biomarker of oxidative stress.
Additional information: Protein G purified IgG2B in PBS, pH 7,4 with 0,09 % sodium azide and 50 % glycerol at concentration 0,65 mg/mL
抗原
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