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XIAP 抗体 (AA 15-244)

XIAP 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886770
发货至: 中国
  • 抗原 See all XIAP 抗体
    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
    抗原表位
    • 16
    • 12
    • 12
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-244
    适用
    • 81
    • 44
    • 30
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 70
    • 12
    • 1
    克隆类型
    • 71
    • 10
    多克隆
    标记
    • 50
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XIAP antibody is un-conjugated
    应用范围
    • 69
    • 34
    • 25
    • 18
    • 15
    • 13
    • 13
    • 12
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase XIAP(XIAP) detection. Tested with WB in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase XIAP(XIAP) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: X-linked inhibitor of apoptosis
    Protein Name: E3 ubiquitin-protein ligase XIAP
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human XIAP recombinant protein (Position: A15-V244). Human XIAP shares 89.4% and 90.7% amino acid (aa) sequence identity with mouse and rat XIAP, respectively.
    亚型
    IgG
    Top Product
    Discover our top product XIAP Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Chen, Mao, Qiu, Liu: "Gene transfection mediated by polyethyleneimine-polyethylene glycol nanocarrier prevents cisplatin-induced spiral ganglion cell damage." in: Neural regeneration research, Vol. 10, Issue 3, pp. 425-31, (2015) (PubMed).

  • 抗原
    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
    别名
    XIAP (XIAP 产品)
    别名
    API3 antibody, BIRC4 antibody, IAP-3 antibody, ILP1 antibody, MIHA antibody, XLP2 antibody, hIAP-3 antibody, hIAP3 antibody, api3 antibody, birc4 antibody, ilp1 antibody, miha antibody, xlp2 antibody, xxiap antibody, 1110015C02Rik antibody, Aipa antibody, Api3 antibody, Birc4 antibody, IAP3 antibody, ILP-1 antibody, mXIAP antibody, riap3 antibody, fb73d01 antibody, wu:fb73d01 antibody, zgc:91873 antibody, BIRC8 antibody, X-linked inhibitor of apoptosis antibody, X-linked inhibitor of apoptosis L homeolog antibody, XIAP antibody, xiap antibody, xiap.L antibody, Xiap antibody
    背景
    XIAP, also known as IAP3 or BIRC4, is a protein that stops apoptotic cell death. It is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants.

    Synonyms: API3 | Api3 | Birc4 | API 3 | BIRC4 | IAP3 | BIRC 4 | E3 ubiquitin-protein ligase XIAP | hIAP3 | hIAP-3 | HILP | IAP 3 | IAP-like protein | ILP 1 | X linked IAP | X-linked IAP | X-linked inhibitor of apoptosis | XLP2 | P98170
    基因ID
    331
    UniProt
    P98170
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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