电话:: +86 (0512) 65829739
传真:: +86 (010) 6788 5057
电子邮件:: orders@antibodies-online.cn

我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

PML 抗体 (N-Term)

This anti-PML antibody is a 兔多克隆 antibody detecting PML in WB, IHC 和 FACS. Suitable for 人.

Western blot analysis of PML Protein expression in SW620 whole cell lysates ( Lane 1) and U2OS whole cell lysates ( Lane 2). (PML 抗体 (N-Term))

PML Protein was detected in paraffin-embedded sections of human intetsinal cancer tissues using rabbit anti- PML Protein Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 ? (PML 抗体 (N-Term))

2 images

产品编号 ABIN4886699

发货至: 中国

Quick Overview for PML 抗体 (N-Term) (ABIN4886699)

抗原

See all PML 抗体

PML (Promyelocytic Leukemia (PML))

适用

75
25
22
2
2
2
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

51
5
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This PML antibody is un-conjugated

应用范围

60
33
19
18
12
12
11
11
8
2
2
2
2
1
1

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Discover our top product PML Primary Antibody

抗原表位
13

8

5

5

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 141-179, N-Term

原理

Anti-PML Protein Antibody Picoband®

序列

FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLD

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-PML Protein Antibody Picoband® (ABIN4886699). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human PML Protein, different from the related mouse sequence by eight amino acids.

亚型

IgG
anti-Promyelocytic Leukemia (PML) (AA 411-510) antibody
PML 适用: 人 WB, IF, ELISA, PLA 宿主: 小鼠 Monoclonal 1D12 unconjugated

anti-Promyelocytic Leukemia (PML) (N-Term) antibody
PML 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 470-499), (Sumoylation Site) antibody
PML 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 300-600) antibody
PML 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (C-Term) antibody
PML 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 411-510) antibody
PML 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2B10 unconjugated

anti-Promyelocytic Leukemia (PML) (C-Term) antibody
PML 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 470-499), (Sumoylation Site) antibody
PML 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB2570 unconjugated

anti-Promyelocytic Leukemia (PML) (N-Term) antibody
PML 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Promyelocytic Leukemia (PML) (AA 588-637) antibody
PML 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. Dyck, J. A., Maul, G. G., Miller, W. H., Jr., Chen, J. D., Kakizuka, A., Evans, R. M. A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell 76: 333-343, 1994. 2. Giorgi, C., Ito, K., Lin, H.-K., Santangelo, C., Wieckowski, M. R., Lebiedzinska, M., Bononi, A., Bonora, M., Duszynski, J., Bernardi, R., Rizzuto, R., Tacchetti, C., Pinton, P., Pandolfi, P. P. PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science 330: 1247-1251, 2010.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

PML (Promyelocytic Leukemia (PML))

别名

PML

背景

Synonyms: Protein PML,Promyelocytic leukemia protein,RING finger protein 71,Tripartite motif-containing protein 19,PML,MYL, PP8675, RNF71, TRIM19,
Tissue Specificity: Milk lipid globules.
Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions, all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified.

分子量

90-160 kDa

基因ID

5371

UniProt

P29590

途径

p53 Pathway, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus

You are here: