Cytokeratin 5 抗体 (Middle Region)
Quick Overview for Cytokeratin 5 抗体 (Middle Region) (ABIN4886654)
抗原
See all Cytokeratin 5 (KRT5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 286-317, Middle Region
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原理
- Anti-Cytokeratin 5/KRT5 Antibody Picoband®
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序列
- KVELEAKVDA LMDEINFMKM FFDAELSQMQ TH
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cytokeratin 5/KRT5 Antibody Picoband® (ABIN4886654). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Cytokeratin 5, different from the related mouse sequence by one amino acid, and identical to the related rat sequence.
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亚型
- IgG
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anti-Keratin 5 (KRT5) (AA 316-590) antibody
KRT5 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 10C11E6 unconjugated
anti-Keratin 5 (KRT5) antibodyKRT5 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2C2 unconjugated
anti-Keratin 5 (KRT5) (AA 335-473) antibodyKRT5 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 316-590) antibodyKRT5 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal KRT5-3594 unconjugated
anti-Keratin 5 (KRT5) (AA 1-273) antibodyKRT5 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-Keratin 5 (KRT5) antibodyKRT5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 258-357) antibodyKRT5 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2C8E4 unconjugated
anti-Keratin 5 (KRT5) (AA 331-430) antibodyKRT5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (AA 163-471) antibodyKRT5 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 5 (KRT5) (C-Term) antibodyKRT5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
1. "Entrez Gene: KRT5 keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types)". 2. Eckert RL, Rorke EA (Jun 1988). "The sequence of the human epidermal 58-kD (#5) type II keratin reveals an absence of 5' upstream sequence conservation between coexpressed epidermal keratins". Dna. 7 (5): 337-45. 3. Lersch R, Fuchs E (Jan 1988). "Sequence and expression of a type II keratin, K5, in human epidermal cells". Molecular and Cellular Biology. 8 (1): 486-93. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
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别名
- KRT5
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背景
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Synonyms: Keratin, type II cytoskeletal 5,58 kDa cytokeratin,Cytokeratin-5,CK-5,Keratin-5,K5,Type-II keratin Kb5,KRT5,
Tissue Specificity: Present in kidney, lung, testis and placenta, very low levels in liver.
Background: Cytokeratin 5, also known as KRT5, K5, or CK5, is a protein that is encoded in humans by the KRT5 gene. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
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分子量
- 62 kDa
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基因ID
- 3852
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UniProt
- P13647
抗原
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