Kallikrein 8 抗体 (AA 33-260)
Quick Overview for Kallikrein 8 抗体 (AA 33-260) (ABIN4886649)
抗原
See all Kallikrein 8 (KLK8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-260
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原理
- Anti-Kallikrein 8/KLK8 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Kallikrein 8/KLK8 Antibody Picoband® (ABIN4886649). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Kallikrein 8 recombinant protein (Position: V33-G260). Human Kallikrein 8 shares 74% and 73.1% amino acid (aa) sequence identity with mouse and rat Kallikrein 8, respectively.
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亚型
- IgG
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anti-Kallikrein 8 (KLK8) antibody
KLK8 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 10D3 unconjugated
anti-Kallikrein 8 (KLK8) antibodyKLK8 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 16G2 unconjugated
anti-Kallikrein 8 (KLK8) antibodyKLK8 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Kallikrein 8 (KLK8) (AA 29-260) antibodyKLK8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 8 (KLK8) (AA 97-204) antibodyKLK8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Kallikrein 8 (KLK8) (AA 51-150) antibodyKLK8 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 8 (KLK8) (AA 87-241) antibodyKLK8 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 8 (KLK8) (AA 1-260) antibodyKLK8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 8 (KLK8) (AA 33-260) antibodyKLK8 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 12C6 unconjugated
anti-Kallikrein 8 (KLK8) (Cleaved-Val33) antibodyKLK8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: KLK8 kallikrein-related peptidase 8". 2. Diamandis, Eleftherios P., Deperthes, David, Lundwall, Åke (Jun 2006). "Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005". Biol Chem 387 (6): 635-824. 3. Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, Stephan C, Talieri M, Yousef GM (Jun 2006). "A comprehensive nomenclature for serine proteases with homology to tissue kallikreins". Biol Chem 387(6): 637-41. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Kallikrein 8 (KLK8)
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别名
- KLK8
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背景
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Synonyms: Kallikrein-8,hK8,3.4.21.118,Neuropsin,NP,Ovasin,Serine protease 19,Serine protease TADG-14,Tumor-associated differentially expressed gene 14 protein,KLK8,NRPN, PRSS19, TADG14,UNQ283/PRO322,
Tissue Specificity: Isoform 1 is predominantly expressed in the pancreas. Isoform 2 is expressed in adult brain and hippocampus. Isoform 1 and isoform 2 are found in fetal brain and placenta. Detected in salivary gland, uterus, thymus, breast, testis and kidney but not in spleen, liver, lung or normal ovarian tissue. Displays an 11.5-fold increase in Alzheimer disease hippocampus compared to controls and is overexpressed in some ovarian carcinomas. Expressed at low levels in normal skin while high levels are found in psoriasis vulgaris, seborrheic keratosis, lichen planus and squamous cell carcinoma skin samples. Expressed in the keratinocytes. .
Background: Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
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分子量
- 28 kDa
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基因ID
- 11202
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UniProt
- O60259
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途径
- Complement System
抗原
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