ILK 抗体 (AA 1-203)
Quick Overview for ILK 抗体 (AA 1-203) (ABIN4886633)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-203
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原理
- Anti-Integrin linked ILK Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Integrin linked ILK Antibody Picoband® (ABIN4886633). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Integrin linked ILK recombinant protein (Position: M1-H203). Human Integrin linked ILK shares 99.5% amino acid (aa) sequence identity with both mouse and rat Integrin linked ILK.
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亚型
- IgG
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anti-Integrin-Linked Kinase (ILK) antibody
KO Validated ILK 适用: 人 WB, IHC, IHC (p), IP, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 97-244) antibodyILK 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 341-452) antibodyILK 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 301-400) antibodyILK 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 1-260) antibodyILK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 225-253) antibodyILK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 11-41) antibodyILK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (pThr173) antibodyILK 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (AA 1-228) antibodyILK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin-Linked Kinase (ILK) (C-Term) antibodyILK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: ILK integrin-linked kinase". 2. Fielding AB, Dobreva I, McDonald PC, Foster LJ, Dedhar S (Feb 2008). "Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization". The Journal of Cell Biology 180 (4): 681-9. 3. Melchior, C., Kreis, S., Janji, B., Kieffer, N. Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1. Biochim. Biophys. Acta 1575: 117-122, 2002. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ILK (Integrin-Linked Kinase (ILK))
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别名
- ILK
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背景
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Synonyms: Integrin-linked protein kinase,2.7.11.1,59 kDa serine/threonine-protein kinase,ILK-1,ILK-2,p59ILK,ILK,ILK1, ILK2,
Tissue Specificity: Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.
Background: ILK, also known as Integrin-linked kinase, is a serine-threonine protein kinase. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/ threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.
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分子量
- 55 kDa
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基因ID
- 3611
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UniProt
- Q13418
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
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