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FGG 抗体 (N-Term)

This anti-FGG antibody is a 兔 多克隆 antibody detecting FGG in WB, IHC, ICC, FACS 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4886589
发货至: 中国

Quick Overview for FGG 抗体 (N-Term) (ABIN4886589)

抗原

See all FGG 抗体
FGG (Fibrinogen gamma Chain (FGG))

适用

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人, 小鼠, 大鼠

宿主

  • 97
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克隆类型

  • 90
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多克隆

标记

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This FGG antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
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    AA 133-163, N-Term

    原理

    Anti-Fibrinogen gamma chain/FGG Antibody Picoband®

    序列

    IRYLQEIYNS NNQKIVNLKE KVAQLEAQCQ E

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Fibrinogen gamma chain/FGG Antibody Picoband® (ABIN4886589). Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human FGG, different from the related mouse sequence by two amino acids, and from the related rat sequence by five amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
    Immunocytochemistry, 0.5-1 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Budzynski, A. Z., Marder, V. J., Menache, D., Guillin, M.-C. Defect in the gamma polypeptide chain of a congenital abnormal fibrinogen (Paris I). Nature 252: 66-68, 1974. 2. Ebert, R. F., Bell, W. R. Fibrinogen Baltimore III: congenital dysfibrinogenemia with a shortened gamma-subunit. Thromb. Res. 51: 251-258, 1988. 3. Fornace, A. J., Jr., Cummings, D. E., Comeau, C. M., Kant, J. A., Crabtree, G. R. Structure of the human gamma-fibrinogen gene: alternate mRNA splicing near the 3-prime end of the gene produces gamma-A and gamma-B forms of gamma-fibrinogen. J. Biol. Chem. 259: 12826-12830, 1984.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    FGG (Fibrinogen gamma Chain (FGG))

    别名

    FGG

    背景

    Synonyms: Fibrinogen gamma chain,FGG,PRO2061,

    Tissue Specificity: Detected in blood plasma (at protein level). .

    Background: Fibrinogen gamma chain, also known as FGG, is a human gene found on Chromosome 4. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

    分子量

    52 kDa

    基因ID

    2266

    UniProt

    P02679
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