Diazepam Binding Inhibitor 抗体 (AA 2-87)
Quick Overview for Diazepam Binding Inhibitor 抗体 (AA 2-87) (ABIN4886558)
抗原
See all Diazepam Binding Inhibitor (DBI) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-87
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原理
- Anti-Diazepam Binding Inhibitor/DBI Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Diazepam Binding Inhibitor/DBI Antibody Picoband® (ABIN4886558). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human DBI recombinant protein (Position: S2-I87). Human DBI shares 77.9% amino acid (aa) sequence identity with both mouse and rat DBI.
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亚型
- IgG
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anti-Diazepam Binding Inhibitor (DBI) (AA 2-87) antibody
DBI 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) (AA 1-114) antibodyDBI 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) (AA 1-104) antibodyDBI 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) antibodyDBI 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) (N-Term) antibodyDBI 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) (AA 2-187) antibodyDBI 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) (AA 2-105) antibodyDBI 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) (AA 1-104) antibodyDBI 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) (N-Term) antibodyDBI 适用: 人, 小鼠, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Diazepam Binding Inhibitor (DBI) (C-Term) antibodyDBI 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: DBI diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)". 2. Mandrup S, Hummel R, Ravn S, et al. (1993). "Acyl-CoA-binding protein/diazepam-binding inhibitor gene and pseudogenes. A typical housekeeping gene family". J. Mol. Biol. 228 (3): 1011-22. 3. Todd S, Naylor SL (Dec 1992). "New chromosomal mapping assignments for argininosuccinate synthetase pseudogene 1, interferon-beta 3 gene, and the diazepam binding inhibitor gene". Somat Cell Mol Genet. 18(4): 381-5. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Diazepam Binding Inhibitor (DBI)
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别名
- DBI
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背景
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Synonyms: Acyl-CoA-binding protein,ACBP,Diazepam-binding inhibitor,DBI,Endozepine,EP,DBI,
Tissue Specificity: Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. .
Background: Acyl-CoA-binding protein is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
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分子量
- 10 kDa
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基因ID
- 1622
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UniProt
- P07108
抗原
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