Cofilin 2 抗体 (C-Term)
Quick Overview for Cofilin 2 抗体 (C-Term) (ABIN4886538)
抗原
See all Cofilin 2 (CFL2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-153, C-Term
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原理
- Anti-Cofilin 2/CFL2 Antibody Picoband®
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序列
- KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKL
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cofilin 2/CFL2 Antibody (ABIN4886538). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cofilin 2, identical to the related mouse sequence.
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亚型
- IgG
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anti-Cofilin 2 (CFL2) (AA 57-166) antibody
CFL2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6G9 unconjugated
anti-Cofilin 2 (CFL2) (C-Term) antibodyVerified CFL2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (C-Term) antibodyCFL2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-166) antibodyCFL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-156) antibodyCFL2 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 130-144), (C-Term) antibodyCFL2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB48609 unconjugated
anti-Cofilin 2 (CFL2) antibodyCFL2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-166) antibodyCFL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (C-Term) antibodyCFL2 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 马, Pig, 猴, Bat, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 25-54), (N-Term) antibodyCFL2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: CFL2 cofilin 2 (muscle)". 2. Agrawal PB, Greenleaf RS, Tomczak KK, Lehtokari VL, Wallgren-Pettersson C, Wallefeld W, Laing NG, Darras BT, Maciver SK, Dormitzer PR, Beggs AH (January 2007). "Nemaline myopathy with minicores caused by mutation of the CFL2 gene encoding the skeletal muscle actin-binding protein, cofilin-2". Am. J. Hum. Genet. 80 (1): 162-7. 3. Gillett GT, Fox MF, Rowe PS, Casimir CM, Povey S (May 1996). "Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14". Ann. Hum. Genet. 60 (Pt 3): 201-11. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Cofilin 2 (CFL2)
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别名
- CFL2
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背景
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Synonyms: Cofilin-2,Cofilin, muscle isoform,CFL2,
Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Background: Cofilin 2 (muscle), also known as CFL2, is a protein which in humans is encoded by the CFL2 gene. It is mapped to 14q12. This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. And this protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
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分子量
- 26 kDa
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基因ID
- 1073
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UniProt
- Q9Y281
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途径
- Caspase Cascade in Apoptosis
抗原
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