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- 抗原 See all Complement Factor I (CFI) 抗体
- Complement Factor I (CFI)
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抗原表位
- AA 19-220
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Complement Factor I antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Complement factor I(CFI) detection. Tested with WB in Human,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Complement factor I(CFI) detection. Tested with WB in Human,Rat.
Gene Name: complement factor I
Protein Name: Complement factor I - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human Factor I recombinant protein (Position: K19-D220). Human Factor I shares 70.7% and 71.2% amino acid (aa) sequence identity with mouse and rat Factor I, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product CFI Primary Antibody
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anti-Complement Factor I (CFI) (AA 28-243) antibody
CFI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 358-603) antibodyCFI 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Complement Factor I (CFI) (AA 239-316) antibodyCFI 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 340-583) antibodyCFI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Factor I (CFI) antibodyCFI 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 145-194) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Complement Factor I (CFI)
- 别名
- CFI (CFI 产品)
- 背景
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Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene.
Synonyms: AHUS3 | ARMD13 | C3b INA | C3BINA | C3b inactivator | C3B/C4B inactivator | Cfi | Complement component I | Complement factor I | F1 | factorI | factor I | I factor | IF | KAF | P05156 - 基因ID
- 3426
- UniProt
- P05156
- 途径
- Complement System
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