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CD40 抗体 (AA 21-193)

This anti-CD40 antibody is a 兔多克隆 antibody detecting CD40 in FACS, WB, ELISA 和 IHC. Suitable for 人.

Western blot analysis of CD40/TNFRSF5 expression in RAJI whole cell lysates ( Lane 1). (CD40 抗体 (AA 21-193))

1 image

产品编号 ABIN4886525

发货至: 中国

Quick Overview for CD40 抗体 (AA 21-193) (ABIN4886525)

抗原

See all CD40 抗体

CD40

适用

216
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25
19
8
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2
2
1

人

宿主

兔

克隆类型

多克隆

标记

This CD40 antibody is un-conjugated

应用范围

196
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23
20
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5
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1

Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Discover our top product CD40 Primary Antibody

抗原表位
20

18

17

16

14

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14

11

9

5

3

2

2

1

1

1

1

1

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1

1
AA 21-193

原理

Anti-CD40 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-CD40 Antibody Picoband® (ABIN4886525). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human CD40/TNFRSF5 recombinant protein (Position: E21-R193). Human CD40/TNFRSF5 shares 60.2% amino acid (aa) sequence identity with mouse CD40/TNFRSF5.

亚型

IgG
anti-CD40 (CD40) (AA 26-187) antibody
CD40 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD40 (CD40) antibody
CD40 适用: 人 FACS, IHC, IF, StM, DNA Mic 宿主: 小鼠 Monoclonal C40-1605 unconjugated

anti-CD40 (CD40) (AA 29-107) antibody
CD40 适用: 人 FACS, ELISA, IHC, StM, Coat 宿主: 小鼠 Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (C-Term) antibody
CD40 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD40 (CD40) (AA 21-193) antibody
CD40 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4C3B8 unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 适用: 人 FACS, IHC, St 宿主: 小鼠 Monoclonal 5C3 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD40 (CD40) antibody
CD40 适用: 人 FACS, IHC, IP, Act 宿主: 兔 Chimeric G28-5 unconjugated Recombinant Antibody

anti-CD40 (CD40) antibody
CD40 适用: 人 FACS 宿主: 小鼠 Monoclonal HI40a unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 适用: 人 FACS 宿主: 小鼠 Monoclonal HI40a FITC

应用备注

Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Clark, E. A. : CD40: a cytokine receptor in search of a ligand. Tissue Antigens 35: 33-36, 1990. 2. Harding, S. A., Sarma, J., Josephs, D. H., Cruden, N. L., Din, J. N., Twomey, P. J., Fox, K. A. A., Newby, D. E. : Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers. Circulation 109: 1926-1929, 2004. 3. Kato, K., Cantwell, M. J., Sharma, S., Kipps, T. J. : Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells. J. Clin. Invest. 101: 1133-1141, 1998. 4. Stamenkovic, I., Clark, E. A., Seed, B. : A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J. 8: 1403-1410, 1989. 5. van Kooten, C., Banchereau, J. : CD40-CD40 ligand. J. Leuko. Biol. 67: 2-17, 2000.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

CD40

别名

CD40

背景

Synonyms: Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,Bp50,CD40L receptor,CDw40,CD40,CD40,TNFRSF5,
Tissue Specificity: B-cells and in primary carcinomas.
Background: CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. It is a member of the tumor necrosis factor (TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.

分子量

43 kDa

基因ID

958

UniProt

P25942

途径

NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints

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