CCT4 抗体 (AA 452-539)
Quick Overview for CCT4 抗体 (AA 452-539) (ABIN4886514)
抗原
See all CCT4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 452-539
-
原理
- Anti-TCP1 delta/CCT4 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-TCP1 delta/CCT4 Antibody Picoband® (ABIN4886514). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human CCT4 recombinant protein (Position: R452-R539). Human CCT4 shares 97.7% amino acid (aa) sequence identity with both mouse and rat CCT4.
-
亚型
- IgG
-
-
anti-Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4) (AA 130-390) antibody
CCT4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4) (C-Term) antibodyCCT4 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4) antibodyCCT4 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4) antibodyCCT4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4) (AA 453-502) antibodyCCT4 适用: 人, 小鸡, Drosophila melanogaster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4) (AA 79-378) antibodyCCT4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4) antibodyCCT4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Lee, M.-J., Stephenson, D. A., Groves, M. J., Sweeney, M. G., Davis, M. B., An, S.-F., Houlden, H., Salih, M. A. M., Timmerman, V., de Jonghe, P., Auer-Grumbach, M., Di Maria, E., Scaravilli, F., Wood, N. W., Reilly, M. M. Hereditary sensory neuropathy is caused by a mutation in the delta subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct4) gene. Hum. Molec. Genet. 12: 1917-1925, 2003. 2. Won, K.-A., Schumacher, R. J., Farr, G. W., Horwich, A. L., Reed, S. I. Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT. Molec. Cell. Biol. 18: 7584-7589, 1998. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))
-
别名
- CCT4
-
背景
-
Synonyms: T-complex protein 1 subunit delta,TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding,CCT4,CCTD, SRB,
Tissue Specificity: Expressed in the temporal lobe, frontal lobe, parietal lobe, hippocampus, and cerebellum. Also found in kidney, lung, liver, heart, skeletal muscle, placenta. .
Background: T-complex protein 1 subunit delta is a protein that in humans is encoded by the CCT4 gene. This gene is mapped to 2p15. The chaperonin containing TCP1 complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin and tubulin, as well as alpha-transducin.
-
分子量
- 58 kDa
-
基因ID
- 10575
-
UniProt
- P50991
-
途径
- Embryonic Body Morphogenesis
抗原
-
