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CGRP 抗体 (C-Term)

This anti-CGRP antibody is a 兔 多克隆 antibody detecting CGRP in IHC. Suitable for 大鼠 和 小鼠.
产品编号 ABIN4886497
发货至: 中国

Quick Overview for CGRP 抗体 (C-Term) (ABIN4886497)

抗原

See all CGRP (CALCA) 抗体
CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

适用

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大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CGRP antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    • 2
    • 2
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    AA 83-119, C-Term

    原理

    Anti-Calcitonin/CALCA Antibody

    序列

    SCNTATCVTH RLAGLLSRSG GVVKDNFVPT NVGSEAF

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Calcitonin/CALCA Antibody Picoband® (ABIN4886497). Tested in IHC applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Calcitonin, different from the related human sequence by four amino acids, and identical to the related rat sequence.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
    1. Alevizaki, M., Stevenson, J. C., Girgis, S. I., MacIntyre, I., Legon, S. Altered calcitonin gene in a young patient with osteoporosis.Brit. Med. J. 298: 1215-1216, 1989. Note: Retraction: Brit. Med. J. 299: 235 only, 1989. 2. Breimer, L. H., MacIntyre, I., Zaidi, M. Peptides from the calcitonin genes: molecular genetics, structure and function. Biochem. J. 255: 377-390, 1988. 3. Edbrooke, M. R., Parker, D., McVey, J. H., Riley, J. H., Sorenson, G. D., Pettengill, O. S., Craig, R. K. Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma. EMBO J. 4: 715-724, 1985.

    说明

    Antibody can be supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

    别名

    Calca

    背景

    Synonyms: Calcitonin gene-related peptide 1,Alpha-type CGRP,Calcitonin gene-related peptide I,CGRP-I,Calca,Calc,

    Tissue Specificity: Detected in nerve cells of cerebrum, hippocampus and pons/midbrain in newborns, and only in nerve cells of pons/midbrain in adult. .

    Background: Calcitonin, also known as CALCA, is a peptide hormone synthesized by the parafollicular cells of the thyroid. It is mapped to 11p15.2. Calcitonin belongs to the calcitonin-like protein family. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    75 kDa, 45 kDa

    基因ID

    12310

    途径

    Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour
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