BDKRB2 抗体 (C-Term)
Quick Overview for BDKRB2 抗体 (C-Term) (ABIN4886484)
抗原
See all BDKRB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 357-391, C-Term
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原理
- Anti-BDKRB2 Antibody Picoband®
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序列
- RSEPIQMENS MGTLRTSISV ERQIHKLQDW AGSRQ
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-BDKRB2 Antibody Picoband® (ABIN4886484). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human BDKRB2, different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Fernandes L, Fortes ZB, Nigro D, Tostes RC, Santos RA, Catelli De Carvalho MH (2001). "Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneously hypertensive rats studied in vivo".Hypertension 37 (2 Part 2): 703-9. 2. Hess JF, Borkowski JA, Young GS, et al. (1992). "Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor.". Biochem. Biophys. Res. Commun. 184 (1): 260-8. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- BDKRB2 (Bradykinin Receptor B2 (BDKRB2))
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别名
- BDKRB2
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背景
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Synonyms: B2 bradykinin receptor,B2R,BK-2 receptor,BDKRB2,BKR2,
Tissue Specificity: Ubiquitous. Widespread in normal smooth muscle tissue and neurons. .
Background: Bradykinin receptor B2 is a G-protein coupled receptor forbradykinin, encoded by the BDKRB2 gene in humans. This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
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分子量
- 50 kDa
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基因ID
- 624
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UniProt
- P30411
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途径
- ACE Inhibitor Pathway, Negative Regulation of intrinsic apoptotic Signaling
抗原
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