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APRT 抗体 (N-Term)

This 兔 多克隆 anti-APRT antibody specifically detects APRT in WB, IF, ICC 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN4886471
发货至: 中国
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Quick Overview for APRT 抗体 (N-Term) (ABIN4886471)

抗原

See all APRT 抗体
APRT (Adenine Phosphoribosyltransferase (APRT))

适用

  • 50
  • 7
  • 4
  • 2
  • 1
  • 1

宿主

  • 47
  • 3

克隆类型

  • 49
  • 1
多克隆

标记

  • 29
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APRT antibody is un-conjugated

应用范围

  • 36
  • 20
  • 18
  • 9
  • 7
  • 6
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 14
    • 8
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 5-49, N-Term

    原理

    Anti-APRT Antibody

    序列

    ELQLVEQRIR SFPDFPTPGV VFRDISPVLK DPASFRAAIG LLARH

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-APRT Antibody (ABIN4886471). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human APRT, different from the related mouse sequence by ten amino acids, and from the related rat sequence by nine amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    APRT (Adenine Phosphoribosyltransferase (APRT))

    别名

    APRT

    背景

    Synonyms: Adenine phosphoribosyltransferase,APRT,2.4.2.7,APRT,

    Tissue Specificity: Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole.

    Background: Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    20 kDa

    基因ID

    353

    UniProt

    P07741

    途径

    Ribonucleoside Biosynthetic Process
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