ACO2 抗体 (C-Term)
Quick Overview for ACO2 抗体 (C-Term) (ABIN4886417)
抗原
See all ACO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 561-596, C-Term
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原理
- Anti-Aconitase 2/ACO2 Antibody Picoband®
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序列
- TSQRLQLLEP FDKWDGKDLE DLQILIKVKG KCTTDH
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Aconitase 2/ACO2 Antibody Picoband® (ABIN4886417). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Aconitase 2, identical to the related mouse and rat sequences.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: Aconitase 2, mitochondrial". 2. Geurts van Kessel, A. H. M., Westerveld, A., de Groot, P. G., Meera Khan, P., Hagemeijer, A. Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22. Cytogenet. Cell Genet. 28: 169-172, 1980. 3. Mirel, D. B., Marder, K., Graziano, J., Freyer, G., Zhao, Q., Mayeux, R., Wilhelmsen, K. C. Characterization of the human mitochondrial aconitase gene (ACO2). Gene 213: 205-218, 1998. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ACO2 (Aconitase 2, Mitochondrial (ACO2))
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别名
- ACO2
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背景
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Synonyms: Aconitate hydratase, mitochondrial,Aconitase,4.2.1.3,Citrate hydro-lyase,ACO2,
Tissue Specificity: Highly enriched in the brain. Much weaker expression in heart, lung and muscle.
Background: Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene. The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.
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分子量
- 85 kDa
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基因ID
- 50
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UniProt
- Q99798
抗原
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