ACLY 抗体 (AA 1-180)
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- 抗原 See all ACLY 抗体
- ACLY (ATP Citrate Lyase (ACLY))
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抗原表位
- AA 1-180
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACLY antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- Anti-ATP citrate lyase/ACLY Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-ATP citrate lyase/ACLY Antibody Picoband® (ABIN4886416). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human ATP citrate lyase recombinant protein (Position: M1-I180). Human ATP citrate lyase shares 95% amino acid (aa) sequence identity with both mouse and rat ATP citrate lyase.
- 亚型
- IgG
- Top Product
- Discover our top product ACLY Primary Antibody
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anti-ATP Citrate Lyase (ACLY) (AA 306-502) antibody
ACLY 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5F8D11 unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 752-1101) antibodyACLY 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (pSer455) antibodyACLY 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 306-502) antibodyACLY 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 4-265) antibodyACLY 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) antibodyACLY 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Monoclonal 3A5 unconjugated Recombinant Antibody
anti-ATP Citrate Lyase (ACLY) (C-Term) antibodyACLY 适用: 人, 小鼠 WB, FACS, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (Middle Region) antibodyACLY 适用: 人, 小鼠, 大鼠, Pig, Cow, 兔, 斑马鱼, 绵羊, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) antibodyACLY 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (Ser1227) antibodyACLY 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Fatland BL, Ke J, Anderson MD, Mentzen WI, Cui LW, Allred CC, Johnston JL, Nikolau BJ, Wurtele ES (October 2002). "Molecular characterization of a heteromeric ATP-citrate lyase that generates cytosolic acetyl-coenzyme A in Arabidopsis". Plant Physiol. 130 (2): 740-756. 2. Guay C, Madiraju SR, Aumais A, Joly E, Prentki M (December 2007). "A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion". J. Biol. Chem. 282 (49): 35657-35665. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- ACLY (ATP Citrate Lyase (ACLY))
- 别名
- ACLY (ACLY 产品)
- 背景
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Synonyms: ATP-citrate synthase,2.3.3.8,ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme,ACLY,
Background: ATP citrate lyase, aslo known as ACLY, is an enzyme that in animals represents an important step in fatty acid biosynthesis. ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of apparently identical subunits. The product, acetyl-CoA, in animals serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. It is activated by insulin. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. In plants, ATP citrate lyase generates the acetyl-CoA for cytosolically-synthesized metabolites.
- 分子量
- 125 kDa
- 基因ID
- 47
- UniProt
- P53396
- 途径
- Warburg Effect
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