ABAT 抗体 (AA 388-500)
Quick Overview for ABAT 抗体 (AA 388-500) (ABIN4886408)
抗原
See all ABAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 388-500
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原理
- Anti-ABAT Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ABAT Antibody Picoband® (ABIN4886408). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human ABAT recombinant protein (Position: K388-K500). Human ABAT shares 93.9% and 94.5% amino acid (aa) sequence identity with mouse and rat ABAT, respectively.
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亚型
- IgG
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anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 236-500) antibody
ABAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 29-300) antibodyABAT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) antibodyABAT 适用: 人 WB, IHC (p), IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 151-250) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 29-300) antibodyABAT 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 1-500) antibodyABAT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (C-Term) antibodyABAT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (Internal Region) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 249-500) antibodyABAT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) antibodyABAT 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. De Biase D, Barra D, Simmaco M, John RA, Bossa F (Jan 1995). "Primary structure and tissue distribution of human 4-aminobutyrate aminotransferase". European Journal of Biochemistry / FEBS 227 (1-2): 476-80. 2. Medina-Kauwe LK, Tobin AJ, De Meirleir L, Jaeken J, Jakobs C, Nyhan WL, Gibson KM (Jun 1999). "4-Aminobutyrate aminotransferase (GABA-transaminase) deficiency".Journal of Inherited Metabolic Disease 22 (4): 414-27. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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别名
- ABAT
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背景
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Synonyms: 4-aminobutyrate aminotransferase, mitochondrial,2.6.1.19, (S)-3-amino-2-methylpropionate transaminase,2.6.1.22,GABA aminotransferase,GABA-AT,Gamma-amino-N-butyrate transaminase,GABA transaminase,GABA-T,L-AIBAT,ABAT,GABAT,
Tissue Specificity: Liver > pancreas > brain > kidney > heart > placenta.
Background: 4-Aminobutyrate aminotransferase is a protein that in humans is encoded by the ABAT gene. ABAT is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5- phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of humans ynapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractoryseizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
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分子量
- 54 kDa
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基因ID
- 18
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UniProt
- P80404
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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