FOXP3 抗体
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北京 101111
Quick Overview for FOXP3 抗体 (ABIN487427)
抗原
See all FOXP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The mouse monoclonal antibody 3G3 recognizes N-terminal region of FoxP3, a 47-55 kDa transcription factor, which is the master regulator in the development and function of regulatory T cells.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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产品特性
- Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin
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纯化方法
- Protein A affinity chromatography
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免疫原
- Full-length His-tagged recombinant murine FoxP3
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亚型
- IgG1
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anti-Forkhead Box P3 (FOXP3) (AA 190-412) antibody
FOXP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P3 (FOXP3) (C-Term) antibodyVerified FOXP3 适用: 小鼠 FACS, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box P3 (FOXP3) (AA 297-431) antibodyFOXP3 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 4F12A2 unconjugated
anti-Forkhead Box P3 (FOXP3) (C-Term) antibodyFOXP3 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibodyFOXP3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P3 (FOXP3) (C-Term) antibodyVerified FOXP3 适用: 人 WB, FACS, IHC, ELISA, IF, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box P3 (FOXP3) (AA 275-325) antibodyFOXP3 适用: 人 WB, IHC, IP, ICC, IF (p), mIF 宿主: 兔 Monoclonal BLR034F unconjugated Recombinant Antibody
anti-Forkhead Box P3 (FOXP3) (N-Term) antibodyFOXP3 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 马, 犬, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibodyFOXP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D1 unconjugated
anti-Forkhead Box P3 (FOXP3) (AA 1-431) antibodyFOXP3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow cytometry (Application note see below). Western blot: 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- FOXP3 (Forkhead Box P3 (FOXP3))
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别名
- FOXP3
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背景
- FoxP3 (Forkhead box protein 3), a highly conserved forkhead/winged-helix transcription factor, plays a crucial role in maintaining immune homeostasis by governing the development and function of regulatory T cells. It is constitutively expressed at high level in CD25+ CD4+ Treg cells and at low level in a CD25- CD4+ Treg cell subset. Defects in gene encoding FoxP3 protein cause the scurfy phenotype in mice, and in human the IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome.Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin
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基因ID
- 20371
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UniProt
- Q99JB6
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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