GSK3 alpha 抗体 (AA 203-219)
Quick Overview for GSK3 alpha 抗体 (AA 203-219) (ABIN470870)
抗原
See all GSK3 alpha (GSK3a) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 203-219
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特异性
- Recognizes Glycogen Synthase Kinase 3 (GSK3). Due to extremely high conservation among the known enzymes of many different species, should cross-react with nearly all species homologues. Species cross-reactivity: Mouse, rat, S. pombe, Dictyostelium and human.
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预测反应
- Percent identity by BLAST analysis: Drosophila, Mosquito (100%) Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (88%).
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纯化方法
- Protein G purified
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免疫原
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Synthetic peptide corresponding to aa203-219 (18aa, C-KQLLHGEPNVSYICSRY) derived from a region of the catalytic domain (between subdomain VII and VIII) of the Drosophila GSK-3/ shaggy enzyme (ovalbumin coupled). Percent identity by BLAST analysis: Drosophila, Mosquito (100%), Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (88%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG1
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应用备注
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Approved: ICC (10 μg/mL), WB (0.5 - 2 μg/mL)
Usage: Suitable for use in Western Blot and Immunocytochemistry. Proteins were visualized using an IgG (HRP) goat anti-mouse and a chemiluminescence detection system. Immunocytochemistry: 10 μg/mL. Demonstrated positive immunostaining for GSK3 in L6 cells fixed with acetone. Positive control: J9000: Jurkat Cell. -
说明
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Target Species of Antibody: Drosophila
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
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别名
- GSK3A / GSK3 Alpha
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背景
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Name/Gene ID: GSK3A
Subfamily: GSK-3
Family: Protein Kinase
Synonyms: GSK3A, GSK-3 alpha, GSK3 alpha -
基因ID
- 2931
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UniProt
- P49840
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途径
- PI3K-Akt Signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
抗原
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