HLA-E 抗体
Quick Overview for HLA-E 抗体 (ABIN462415)
抗原
See all HLA-E 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognized native surface-expressed HLA-E, but not denatured heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7
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纯化方法
- Protein A purified
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免疫原
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Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.
Type of Immunogen: Synthetic peptide -
亚型
- IgG1
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应用备注
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Approved: Flo, IHC, IHC-P (10 μg/mL), IP
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Tris buffered saline (TBS), 15 mM sodium azide, approx, pH 8.0. Sourced in Ascites.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
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别名
- HLA-E
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UniProt
- P13747
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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