SPTLC1 抗体
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北京 101111
Quick Overview for SPTLC1 抗体 (ABIN4620353)
抗原
See all SPTLC1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Serine Palmitoyltransferase 1, ubiquitously expressed.
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纯化方法
- Antigen Immunoaffinity Chromatography
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免疫原
- Synthetic peptide derived from the Human Sserine Palmitoyltransferase enzyme
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亚型
- IgG
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应用备注
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Western Blot: (1-5 μg/mL). Immunohistochemistry: (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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别名
- SPTLC1
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背景
- Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.Synonyms: LCB 1, LCB1, Long chain base biosynthesis protein 1, SPT 1, SPT1, Serine palmitoyltransferase 1, Serine-palmitoyl-CoA transferase 1
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分子量
- 52.7 kDa
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基因ID
- 10558
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NCBI登录号
- NP_006406
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UniProt
- O15269
抗原
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