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Sphingomyelin Synthase 1 抗体

This anti-Sphingomyelin Synthase 1 antibody is a 兔 多克隆 antibody detecting Sphingomyelin Synthase 1 in WB, IHC (fro) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN4620352
发货至: 中国

Quick Overview for Sphingomyelin Synthase 1 抗体 (ABIN4620352)

抗原

See all Sphingomyelin Synthase 1 (SGMS1) 抗体
Sphingomyelin Synthase 1 (SGMS1)

适用

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人, 小鼠

宿主

  • 40

克隆类型

  • 39
  • 1
多克隆

标记

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This Sphingomyelin Synthase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects Sphingomyelin Synthase 1, expressed in brain, heart, kidney, liver, muscle and stomach.

    纯化方法

    Ligand Affinity Chromatography

    免疫原

    Synthetic peptide derived from the Human Sphingomyelin Synthase 1 protein
  • 应用备注

    ELISA. Western Blot: (5-10 g). Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline with 0.08 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Sphingomyelin Synthase 1 (SGMS1)

    别名

    TMEM23 / SGMS1

    背景

    A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus, Golgi membrane, multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.Synonyms: MOB, Medulla oblongata-derived protein, Phosphatidylcholine:ceramide cholinephosphotransferase 1, SMS1, Sphingomyelin synthase 1, Transmembrane protein 23

    基因ID

    259230

    NCBI登录号

    NP_671512

    UniProt

    Q86VZ5

    途径

    Cellular Response to Molecule of Bacterial Origin
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