SPHK2 抗体 (Long Isoform, N-Term)
Quick Overview for SPHK2 抗体 (Long Isoform, N-Term) (ABIN4620350)
抗原
See all SPHK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Long Isoform, N-Term
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特异性
- This antibody detetcts Sphingosine Kinase 2 (Long Form).
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纯化方法
- Ligand affinity chromatography
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免疫原
- Synthetic peptide derived from the N-terminal extension of the Sphingosine Kinase 2-L protein
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亚型
- IgG
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anti-Sphingosine Kinase 2 (SPHK2) (AA 590-620), (C-Term) antibody
SPHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03625 unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-654) antibodySPHK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 101-200) antibodySPHK2 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (N-Term) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) antibodySPHK2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-654) antibodySPHK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (Tyr754) antibodySPHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-30), (N-Term) antibodySPHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03623 unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-30) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 590-620) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: (1-5 μg/mL). Positive control: Jurkat lysate. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon arrival, aliquot and freeze at -20 °C to -70 °C.
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- SPHK2 (Sphingosine Kinase 2 (SPHK2))
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别名
- Sphingosine Kinase 2 / SPK2
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背景
- The long form of sphingosine kinase 2 (Sphk2-L) is a species-specific isoform of the Sphk2 enzyme expressed in human but not in mouse. It is an N-terminal extended form of Sphk2, extended by 36 amino acids. It functions as expected, catalyzing the formation of sphingosine 1-phosphate from sphingosine, however it appears to have a decreased ability to inhibit DNA synthesis as compared to Sphk2-S (short form of Sphk2). Under normal cellular conditions, Sphk2-L does not appear to inhibit DNA synthesis, but under serum deprivation, SphK2-L translocates to the nucleus and accumlates. This accumlation may be involved in the cessation of cell proliferation or apoptosis depending on the cell type.Synonyms: SK2, SPHK2
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基因ID
- 56848
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NCBI登录号
- NP_064511
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UniProt
- Q9NRA0
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途径
- VEGF Signaling
抗原
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