C6 抗体 (C-Term)
Quick Overview for C6 抗体 (C-Term) (ABIN461987)
抗原
See all C6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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品牌
- IHC-plus™
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特异性
- Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.
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纯化方法
- Protein A purified
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免疫原
- Purified human C6.
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亚型
- IgG1
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anti-Complement Component 6 (C6) (AA 682-934) antibody
C6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 6 (C6) (AA 30-58) antibodyC6 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 6 (C6) (AA 30-58), (N-Term) antibodyC6 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB21849 unconjugated
anti-Complement Component 6 (C6) (Internal Region) antibodyC6 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 6 (C6) antibodyC6 适用: 人 ELISA, FACS, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. Histology Positive Control Tissue: Kidney from post streptococcal glomerulonephritis patients. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Borate buffered saline, 0.09 % sodium azide. Sourced in Ascites.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- C6 (Complement Component 6 (C6))
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别名
- Complement C6
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背景
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Name/Gene ID: C6
Synonyms: C6, Complement component C6, Complement C6, Complement component 6 -
基因ID
- 729
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UniProt
- P13671
抗原
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