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CD81 抗体

This anti-CD81 antibody is a 小鼠 单克隆 antibody detecting CD81 in FACS, WB, IP, IHC (p) 和 ICC. Suitable for 人, 兔 和 Cat. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN457431
发货至: 中国

Quick Overview for CD81 抗体 (ABIN457431)

抗原

See all CD81 抗体
CD81

适用

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人, 兔, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD81 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

克隆位点

M38
  • 原理

    Anti-Hu CD81 Purified

    特异性

    The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

    交叉反应 (详细)

    Human, Feline (Cat), Rabbit

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    MOLT-4 (human T-ALL cell line)

    亚型

    IgG1
  • 应用备注

    Flow cytometry: recommended dilution: 1 μg/mL.
    Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Oka, Kobayashi, Matsumura, Nishio, Nakano, Okamura, Okochi, Minamisawa, Shiba, Saeki: "New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6." in: Cells, Vol. 9, Issue 6, (2020) (PubMed).

    Matsumura, Minamisawa, Suga, Kishita, Akagi, Ichiki, Ichikawa, Shiba: "Subtypes of tumour cell-derived small extracellular vesicles having differently externalized phosphatidylserine." in: Journal of extracellular vesicles, Vol. 8, Issue 1, pp. 1579541, (2019) (PubMed).

    Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

    Imai, Kakizaki, Nishimura, Yoshie: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).

    Imai, Yoshie et al.: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).

    Fukudome, Furuse, Imai, Nishimura, Takagi, Hinuma, Yoshie et al.: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen ..." in: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, (1992) (PubMed).

  • 抗原

    CD81

    别名

    CD81

    背景

    CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

    基因ID

    975

    UniProt

    P60033

    途径

    Inositol Metabolic Process, Hepatitis C
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