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Kallikrein 6 抗体 (C-Term)

KLK6 适用: 小鼠, 大鼠, Cow WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN453970
发货至: 中国
  • 抗原 See all Kallikrein 6 (KLK6) 抗体
    Kallikrein 6 (KLK6)
    抗原表位
    • 15
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 39
    • 18
    • 10
    • 2
    • 1
    • 1
    小鼠, 大鼠, Cow
    宿主
    • 57
    • 5
    • 2
    山羊
    克隆类型
    • 59
    • 5
    多克隆
    标记
    • 28
    • 10
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Kallikrein 6 antibody is un-conjugated
    应用范围
    • 49
    • 22
    • 21
    • 13
    • 13
    • 9
    • 8
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    KEKPGVYTDV CTHIR
    交叉反应 (详细)
    Species reactivity (expected):Rat and Cow.
    Species reactivity (tested):Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from the C-Terminus of Mouse Kallikrein-6 according to NP_035307.1.
    Top Product
    Discover our top product KLK6 Primary Antibody
  • 应用备注
    Peptide ELISA: Kallikrein-6 Antibody Detection limit dilution 1/16000. Western blot: 1-3 μg/mL. Approx 22 kDa band observed in Mouse Liver lysates (calculatedMW of 27.2 kDa according to NP_035307.1). An additional band of unknown identity wasalso consistently observed at 42 kDa. Both bands were successfully blocked by incubationwith the immunising peptide.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    Kallikrein 6 (KLK6)
    别名
    KLK6 / Kallikrein-6 (KLK6 产品)
    别名
    Bssp antibody, Klk7 antibody, PRSS18 antibody, PRSS9 antibody, SP59 antibody, hK6 antibody, Prss9 antibody, AI849898 antibody, BSP antibody, Klk29 antibody, MSP antibody, Prss18 antibody, neurosin antibody, kallikrein related peptidase 6 antibody, kallikrein related-peptidase 6 antibody, kallikrein-6 antibody, KLK6 antibody, Klk6 antibody, LOC100716801 antibody
    背景
    Tissue kallikreins are a family of extracellular serine proteases consisting of 15 members (1, 2). The genes of this family aligned in tandem on chromosome 19q13.4 represent the largest contiguous group of proteases within the human genome. Tissue kallikreins have attracted great interest as potential biomarkers for various cancers, including prostate, ovarian, breast, testicular, and lung (2, 3). Human Kallikrein 6 (hKLK6) is a member of tissue kallikrein family observed in breast and brain tissues, colon carcinoma cells, and oligodedrocytes (1 3). Known protein substrates of hKLK6 are myelin basic protein, the precursor of the Abeta amyloid peptide, and plasminogen. Its physiological functions may include the participation in demyelination processes as well as in the progression of inflammatory disease of the CNS. The level of hKLK6 is reduced in brain extracts of Alzheimer patients and increased in serum of patients with ovarian cancer.Synonyms: Neurosin, PRSS18, PRSS9, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme
    基因ID
    5653
    NCBI登录号
    NP_001012982
    UniProt
    Q92876
    途径
    Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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