Kallikrein 6 抗体 (C-Term)
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Quick Overview for Kallikrein 6 抗体 (C-Term) (ABIN453970)
抗原
See all Kallikrein 6 (KLK6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- KEKPGVYTDV CTHIR
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交叉反应 （详细）
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Species reactivity (expected):Rat and Cow.
Species reactivity (tested):Mouse. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide from the C-Terminus of Mouse Kallikrein-6 according to NP_035307.1.
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anti-Kallikrein 6 (KLK6) (AA 17-244) antibody
KLK6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 91-190) antibodyKLK6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Kallikrein 6 (KLK6) (AA 22-244) antibodyKLK6 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 1-30), (N-Term) antibodyKLK6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB6114 unconjugated
anti-Kallikrein 6 (KLK6) (AA 217-244) antibodyKLK6 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 126-156) antibodyKLK6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB6116 unconjugated
anti-Kallikrein 6 (KLK6) (Internal Region) antibodyVerified KLK6 适用: 人 IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 74-123) antibodyKLK6 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (C-Term) antibodyKLK6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 6 (KLK6) (AA 227-244), (C-Term) antibodyKLK6 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Peptide ELISA: Kallikrein-6 Antibody Detection limit dilution 1/16000. Western blot: 1-3 μg/mL. Approx 22 kDa band observed in Mouse Liver lysates (calculatedMW of 27.2 kDa according to NP_035307.1). An additional band of unknown identity wasalso consistently observed at 42 kDa. Both bands were successfully blocked by incubationwith the immunising peptide.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Kallikrein 6 (KLK6)
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别名
- KLK6 / Kallikrein-6
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背景
- Tissue kallikreins are a family of extracellular serine proteases consisting of 15 members (1, 2). The genes of this family aligned in tandem on chromosome 19q13.4 represent the largest contiguous group of proteases within the human genome. Tissue kallikreins have attracted great interest as potential biomarkers for various cancers, including prostate, ovarian, breast, testicular, and lung (2, 3). Human Kallikrein 6 (hKLK6) is a member of tissue kallikrein family observed in breast and brain tissues, colon carcinoma cells, and oligodedrocytes (1 3). Known protein substrates of hKLK6 are myelin basic protein, the precursor of the Abeta amyloid peptide, and plasminogen. Its physiological functions may include the participation in demyelination processes as well as in the progression of inflammatory disease of the CNS. The level of hKLK6 is reduced in brain extracts of Alzheimer patients and increased in serum of patients with ovarian cancer.Synonyms: Neurosin, PRSS18, PRSS9, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme
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基因ID
- 5653
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NCBI登录号
- NP_001012982
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UniProt
- Q92876
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途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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