RGS1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for RGS1 抗体 (N-Term) (ABIN453811)
抗原
See all RGS1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody reacts to RGS1.
-
纯化方法
- Affinity chromatography on Protein A
-
免疫原
- KLH conjugated synthetic peptide selected from the N-term region of human RGS1
-
-
-
-
应用备注
-
ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
-
别名
- RGS1
-
背景
- RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Synonyms: 1R20, B-cell activation protein BL34, BL34, Early response protein 1R20, IER1, Regulator of G-protein signaling 1
-
基因ID
- 5996
-
NCBI登录号
- NP_002913
-
UniProt
- Q08116
-
途径
- MAPK Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events
抗原
-