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NLRP12 抗体 (C-Term)

NLRP12 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN453767
发货至: 中国
  • 抗原 See all NLRP12 抗体
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    抗原表位
    • 15
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 45
    • 18
    • 14
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 44
    • 3
    • 1
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP12 antibody is un-conjugated
    应用范围
    • 26
    • 23
    • 13
    • 13
    • 9
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to NALP2.
    纯化方法
    Affinity chrmatography on Protein A
    免疫原
    KLH conjugated synthetic peptide selected from the C-terminal region of human NLRP12
    Top Product
    Discover our top product NLRP12 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    别名
    NALP12 (NLRP12 产品)
    背景
    NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes.Synonyms: LRR and PYD domains-containing protein 12, Monarch-1, NACHT, NLRP12, PYPAF7, PYRIN-containing APAF1-like protein 7, RNO, Regulated by nitric oxide
    基因ID
    91662
    NCBI登录号
    NP_150639
    UniProt
    P59046
    途径
    Positive Regulation of Endopeptidase Activity, Inflammasome
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