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MCAM 抗体 (Middle Region)

This anti-MCAM antibody is a 兔 多克隆 antibody detecting MCAM in WB 和 EIA. Suitable for 人.
产品编号 ABIN453743
发货至: 中国

Quick Overview for MCAM 抗体 (Middle Region) (ABIN453743)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

适用

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宿主

  • 107
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克隆类型

  • 116
  • 98
多克隆

标记

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This MCAM antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 24
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    • 9
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    Middle Region

    特异性

    This antibody reacts to CD146.

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation

    免疫原

    KLH conjugated synthetic peptide selected from the Center region of human MCAM
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    CD146

    背景

    MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.Synonyms: A32, CD146, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen

    基因ID

    4162

    NCBI登录号

    NP_006491

    UniProt

    P43121
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