PHD1 抗体 (Middle Region)
(1 reference)Quick Overview for PHD1 抗体 (Middle Region) (ABIN453633)
抗原
See all PHD1 (EGLN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody reacts to EGLN2.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- KLH conjugated synthetic peptide selected from the Center region of human EGLN2
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anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 283-407) antibody
EGLN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 58-107) antibodyEGLN2 适用: 人, Cow, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 150-250) antibodyEGLN2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 1-407) antibodyEGLN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G3 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 194-221) antibodyEGLN2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22708 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (C-Term) antibodyEGLN2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (N-Term) antibodyEGLN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 281-315) antibodyEGLN2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (N-Term) antibodyEGLN2 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (N-Term) antibodyEGLN2 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response." in: Cancer research, Vol. 69, Issue 2, pp. 616-24, (2009) (PubMed).
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: "Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response." in: Cancer research, Vol. 69, Issue 2, pp. 616-24, (2009) (PubMed).
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- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
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别名
- EGLN2 / PHD1
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背景
- EGLN2 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation.Synonyms: EIT6, Egl nine homolog 2, Estrogen-induced tag 6, HIF PH1, HIF-PH1, HIF-prolyl hydroxylase 1, HPH-1, HPH-3, Hypoxia-inducible factor prolyl hydroxylase 1, Prolyl hydroxylase domain-containing protein 1
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基因ID
- 112398
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NCBI登录号
- NP_444274
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UniProt
- Q96KS0
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis
抗原
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