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SKP2 抗体 (Middle Region)

SKP2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN453378
发货至: 中国
  • 抗原 See all SKP2 抗体
    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
    抗原表位
    • 16
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 66
    • 34
    • 32
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 59
    • 8
    • 1
    克隆类型
    • 60
    • 7
    多克隆
    标记
    • 37
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SKP2 antibody is un-conjugated
    应用范围
    • 46
    • 19
    • 18
    • 17
    • 13
    • 13
    • 12
    • 12
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to SKP2.
    纯化方法
    Saturated Ammonium Sulfate (SAS) precipitation
    免疫原
    KLH conjugated synthetic peptide selected from the Center region of human SKP2
    Top Product
    Discover our top product SKP2 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
    别名
    SKP2 / FBXL1 (SKP2 产品)
    别名
    FBXL1 antibody, FBL1 antibody, FLB1 antibody, p45 antibody, RGD1562456 antibody, S-phase kinase-associated protein 2 (p45) antibody, S-phase kinase associated protein 2 antibody, Skp2 antibody, SKP2 antibody
    背景
    SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class, in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas.Synonyms: Cyclin-A/CDK2-associated protein p45, F-box/LRR-repeat protein 1, S-phase kinase-associated protein 2
    基因ID
    6502
    NCBI登录号
    NP_005974
    UniProt
    Q13309
    途径
    Mitotic G1-G1/S Phases
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