GNS 抗体 (Middle Region)
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北京 101111
Quick Overview for GNS 抗体 (Middle Region) (ABIN453065)
抗原
See all GNS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody detects GNS at Center, N189.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide selected from the Center region of human GNS
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应用备注
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Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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别名
- GNS / G6S
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背景
- GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.Synonyms: Glucosamine-6-sulfatase, N-acetylglucosamine-6-sulfatase
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分子量
- 62082 Da
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基因ID
- 2799
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NCBI登录号
- NP_002067
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UniProt
- P15586
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途径
- Glycosaminoglycan Metabolic Process
抗原
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