FKBP4 抗体 (Middle Region)
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- 抗原 See all FKBP4 抗体
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FKBP4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects FKBP4 at Center.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- 免疫原
- KLH conjugated synthetic peptide selected from the Center region of human FKBP4
- Top Product
- Discover our top product FKBP4 Primary Antibody
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anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 301-410) antibody
FKBP4 适用: 人 WB, IP, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 2-459) antibodyFKBP4 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) antibodyFKBP4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) antibodyFKBP4 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 220-459) antibodyFKBP4 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibodyFKBP4 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Hi52C unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibodyFKBP4 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibody (HRP)FKBP4 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Hi52C HRP
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibody (FITC)FKBP4 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Hi52C FITC
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibody (Alkaline Phosphatase (AP))FKBP4 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Hi52C Alkaline Phosphatase (AP)
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- 应用备注
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Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- 别名
- FKBP4 (FKBP4 产品)
- 别名
- HBI antibody, p52 antibody, hsp56 antibody, PPIase antibody, fkbp52 antibody, fkbp59 antibody, MGC81078 antibody, wu:fb34f09 antibody, 59kDa antibody, AL022792 antibody, AW208983 antibody, FKBP-4 antibody, FKBP-52 antibody, FKBP52 antibody, FKPB52 antibody, p59 antibody, FKBP51 antibody, FKBP59 antibody, Hsp56 antibody, P59 antibody, FK506 binding protein 4 antibody, FK506 binding protein 4 S homeolog antibody, FKBP4 antibody, fkbp4.S antibody, fkbp4 antibody, Fkbp4 antibody
- 背景
- FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy.Synonyms: 52 kDa FK506-binding protein, FK506-binding protein 4, FKBP52 protein, FKBP59, HBI, HSP-binding immunophilin, PPIase, Peptidyl-prolyl cis-trans isomerase, Rotamase, p59 protein
- 分子量
- 51805 Da
- 基因ID
- 2288
- NCBI登录号
- NP_002005
- UniProt
- Q02790
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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