CCL2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for CCL2 抗体 (C-Term) (ABIN452821)
抗原
See all CCL2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects MCP1 / CCL2 at C-term.
-
交叉反应 (详细)
- Species reactivity (tested):Human
-
纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
-
免疫原
- KLH conjugated synthetic peptide selected from the C-terminal region of human CCL2
-
-
-
-
应用备注
-
Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
-
- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
-
别名
- MCP1 / CCL2
-
背景
- Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2
-
分子量
- 11025 Da
-
基因ID
- 6347
-
NCBI登录号
- NP_002973
-
UniProt
- P13500
-
途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
-