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CCL2 抗体 (C-Term)

This anti-CCL2 antibody is a 兔 多克隆 antibody detecting CCL2 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN452821
发货至: 中国

Quick Overview for CCL2 抗体 (C-Term) (ABIN452821)

抗原

See all CCL2 抗体
CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CCL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    This antibody detects MCP1 / CCL2 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of human CCL2
  • 应用备注

    Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

    别名

    MCP1 / CCL2

    背景

    Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2

    分子量

    11025 Da

    基因ID

    6347

    NCBI登录号

    NP_002973

    UniProt

    P13500

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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