ELK1 抗体 (pSer383)
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Quick Overview for ELK1 抗体 (pSer383) (ABIN452642)
抗原
See all ELK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer383
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特异性
- Reactive to the un-conjugated serine383 phosphorylated Human ELK-1 peptide fragment, and reactive to the Serine383 phosphorylated Human ELK-1 peptide fragment conjugated to KLH or the peptide- BSA conjugate.Not reactive to KLH or BSA.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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产品特性
- Synonyms: Elk-1, ETS domain-containing protein Elk-1
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Peptide of a phosphorylated fragment of ELK1 (pSer383) conjugated with KLH.
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亚型
- IgG2b
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应用备注
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Indirect ELISA: The suggested antigen Coating quantity is 1 μg/mL of peptide/or peptideconjugating in pH 9.5 carbonate buffer, 100 μL/well.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
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缓冲液
- 0.01 M PBS, pH 7.0 without preservatives
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
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别名
- ELK1
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背景
- ELK1 belongs to the EST transcription factor family. Proteins in the family have a unique DNA binding domain that binds to conserved DNA sequences. Phosphorylation of ELK1 at serine 383 and 389 by mitogen-activated protein kinases (MAPKs) activates ELK1. The binding of ELK1 to target sequences is also regulated by its co-factor, serum response factor (SRF), by alternative splicing, and by SUMOylation. ELK1 regulates the transcription of c-fos and genes encoding cytoskeleton proteins, and was found to play a role in longterm memory formation, drug addiction and other neurological disorders.Synonyms: ETS domain-containing protein Elk-1, Elk-1
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基因ID
- 2002
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UniProt
- P19419
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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