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ELK1 抗体 (pSer383)

This anti-ELK1 antibody is a 小鼠 单克隆 antibody detecting ELK1 in EIA. Suitable for 人.
产品编号 ABIN452642
发货至: 中国

Quick Overview for ELK1 抗体 (pSer383) (ABIN452642)

抗原

See all ELK1 抗体
ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ELK1 antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA)

克隆位点

D7H2
  • 抗原表位

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    pSer383

    特异性

    Reactive to the un-conjugated serine383 phosphorylated Human ELK-1 peptide fragment, and reactive to the Serine383 phosphorylated Human ELK-1 peptide fragment conjugated to KLH or the peptide- BSA conjugate.Not reactive to KLH or BSA.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    产品特性

    Synonyms: Elk-1, ETS domain-containing protein Elk-1

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Peptide of a phosphorylated fragment of ELK1 (pSer383) conjugated with KLH.

    亚型

    IgG2b
  • 应用备注

    Indirect ELISA: The suggested antigen Coating quantity is 1 μg/mL of peptide/or peptideconjugating in pH 9.5 carbonate buffer, 100 μL/well.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

    缓冲液

    0.01 M PBS, pH 7.0 without preservatives

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

    别名

    ELK1

    背景

    ELK1 belongs to the EST transcription factor family. Proteins in the family have a unique DNA binding domain that binds to conserved DNA sequences. Phosphorylation of ELK1 at serine 383 and 389 by mitogen-activated protein kinases (MAPKs) activates ELK1. The binding of ELK1 to target sequences is also regulated by its co-factor, serum response factor (SRF), by alternative splicing, and by SUMOylation. ELK1 regulates the transcription of c-fos and genes encoding cytoskeleton proteins, and was found to play a role in longterm memory formation, drug addiction and other neurological disorders.Synonyms: ETS domain-containing protein Elk-1, Elk-1

    基因ID

    2002

    UniProt

    P19419

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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