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SAA 抗体

This anti-SAA antibody is a 小鼠 单克隆 antibody detecting SAA in EIA. Suitable for 人.
产品编号 ABIN452611
发货至: 中国

Quick Overview for SAA 抗体 (ABIN452611)

抗原

See all SAA 抗体
SAA (Serum Amyloid A (SAA))

适用

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  • 1

宿主

  • 75
  • 54
  • 10
  • 1
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  • 1
小鼠

克隆类型

  • 86
  • 55
单克隆

标记

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This SAA antibody is un-conjugated

应用范围

  • 89
  • 85
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Enzyme Immunoassay (EIA)

克隆位点

132
  • 特异性

    Reacts with natural and recombinant Human SAA. Does not show any cross-reaction with other Human Cytokines or Growth Factors tested such as IL1 beta, IL-8, MCAF, TGF beta and EGF.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    产品特性

    Synonyms: SAA1, SAA2

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Highly purified recombinant Human SAA. Remarks: Molecular Weight: 12 kDa

    亚型

    IgG3
  • 应用备注

    ELISA. Western Blot: Use of this SSA antibody at a concentration of 0.1-0.5 μg will allowvisualization of 100 ng/lane of recombinant Human SAA.

    限制

    仅限研究用
  • 溶解方式

    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

    缓冲液

    0.01 M PBS, pH 7.2 without preservatives

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    SAA (Serum Amyloid A (SAA))

    别名

    Serum Amyloid A Protein (SAA)

    背景

    The Serum Amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.Synonyms: SAA1, SAA2

    基因ID

    6288

    UniProt

    P02735
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