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CRP 抗体

This 小鼠 单克隆 antibody specifically detects CRP in WB 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN452590
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CRP 抗体 (ABIN452590)

抗原

See all CRP 抗体
CRP (C-Reactive Protein (CRP))

适用

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宿主

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小鼠

克隆类型

  • 173
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单克隆

标记

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This CRP antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

S5G1
  • 特异性

    Reactive with Human CRP in Immunoblot and ELISA

    交叉反应 (详细)

    Species reactivity (tested):Human.

    产品特性

    Synonyms: PTX1, C Reactive Protein, Pentraxin-related

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Purified CRP from human pleural fluid.

    亚型

    IgG1
  • 应用备注

    ELISAImmunoblotting (Western).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

    缓冲液

    0.01 M PBS, pH 7.2 without preservatives.

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CRP (C-Reactive Protein (CRP))

    背景

    C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.Synonyms: C Reactive Protein, PTX1, Pentraxin-related

    基因ID

    1401

    UniProt

    P02741

    途径

    Carbohydrate Homeostasis
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