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M-CSF/CSF1 抗体

CSF1 适用: 人 EIA 宿主: 小鼠 Monoclonal 692 unconjugated
产品编号 ABIN452500
发货至: 中国
  • 抗原 See all M-CSF/CSF1 (CSF1) 抗体
    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
    适用
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    宿主
    • 96
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    小鼠
    克隆类型
    • 96
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    单克隆
    标记
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    This M-CSF/CSF1 antibody is un-conjugated
    应用范围
    • 78
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    Enzyme Immunoassay (EIA)
    特异性
    This monoclonal antibody is specifically reactive to rhM-CSF. Does not cross react with BSA or other Human cytokines tested such as IL1 beta, IL-8, IL-16, EGF, G-CSFR, GM-CSF, MCP-1, MCP-3, TGF beta and TNF alpha.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    产品特性
    Synonyms: CSF-1, CSF1, MCSF, Macrophage colony-stimulating factor 1
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Purified recombinant Human M-CSF (rhM-CSF)
    克隆位点
    692
    亚型
    IgG2a
    Top Product
    Discover our top product CSF1 Primary Antibody
  • 应用备注
    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with Double distillated water to adjust the final concentration to 1.00 mg/mL
    缓冲液
    0.01 M PBS, pH 7.2 without preservatives.
    储存液
    Without preservative
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
    别名
    Macrophage Colony Stimulating Factor (M-CSF) (CSF1 产品)
    别名
    CSF-1 antibody, MCSF antibody, C87615 antibody, Csfm antibody, op antibody, csf1-1 antibody, zgc:172186 antibody, CSF1 antibody, csf1-2 antibody, zgc:158436 antibody, colony stimulating factor 1 antibody, colony stimulating factor 1 (macrophage) antibody, colony stimulating factor 1a (macrophage) antibody, macrophage colony-stimulating factor 1 antibody, macrophage colony stimulating factor antibody, colony stimulating factor 1b (macrophage) antibody, CSF1 antibody, Csf1 antibody, csf1a antibody, LOC396599 antibody, LOC100860895 antibody, csf1b antibody
    背景
    Four distinct colony-stimulating factors (CSFs) that promote survival, proliferation and differentiation of bone marrow precursor cells have been well characterized: granulocyte macrophage CSF (GMCSF), granulocyte CSF (GCSF), macrophage CSF (MCSF), and Interleukin-3 (IL-3, Multi CSF). Both GMCSF and IL-3 are multipotential growth factors, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. In contrast, GCSF and MCSF are lineage restricted hematopoietic growth factors, stimulating final mitotic divisions and the terminal cellular maturation of the partially differentiated hematopoietic progenitors. Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF).Synonyms: CSF-1, CSF1, MCSF, Macrophage colony-stimulating factor 1
    基因ID
    1435
    UniProt
    P09603
    途径
    RTK signaling
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