M-CSF/CSF1 抗体
Quick Overview for M-CSF/CSF1 抗体 (ABIN452500)
抗原
See all M-CSF/CSF1 (CSF1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This monoclonal antibody is specifically reactive to rhM-CSF. Does not cross react with BSA or other Human cytokines tested such as IL1 beta, IL-8, IL-16, EGF, G-CSFR, GM-CSF, MCP-1, MCP-3, TGF beta and TNF alpha.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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产品特性
- Synonyms: CSF-1, CSF1, MCSF, Macrophage colony-stimulating factor 1
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Purified recombinant Human M-CSF (rhM-CSF)
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亚型
- IgG2a
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anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-204) antibody
CSF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) antibodyCSF1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 201-300) antibodyCSF1 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (Middle Region) antibodyCSF1 适用: 人, 小鼠, 大鼠, 犬, Pig, 豚鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-132) antibodyCSF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 261-427) antibodyCSF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 230-257) antibodyCSF1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18764 unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (C-Term) antibodyCSF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-554) antibodyCSF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) antibody (Biotin)CSF1 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
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应用备注
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with Double distillated water to adjust the final concentration to 1.00 mg/mL
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缓冲液
- 0.01 M PBS, pH 7.2 without preservatives.
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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别名
- Macrophage Colony Stimulating Factor (M-CSF)
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背景
- Four distinct colony-stimulating factors (CSFs) that promote survival, proliferation and differentiation of bone marrow precursor cells have been well characterized: granulocyte macrophage CSF (GMCSF), granulocyte CSF (GCSF), macrophage CSF (MCSF), and Interleukin-3 (IL-3, Multi CSF). Both GMCSF and IL-3 are multipotential growth factors, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. In contrast, GCSF and MCSF are lineage restricted hematopoietic growth factors, stimulating final mitotic divisions and the terminal cellular maturation of the partially differentiated hematopoietic progenitors. Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF).Synonyms: CSF-1, CSF1, MCSF, Macrophage colony-stimulating factor 1
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基因ID
- 1435
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UniProt
- P09603
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途径
- RTK signaling
抗原
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