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PPP2R4 抗体 (C-Term)

This anti-PPP2R4 antibody is a 山羊 多克隆 antibody detecting PPP2R4 in WB 和 EIA. Suitable for 人, 小鼠, 大鼠, Cow 和 犬.
产品编号 ABIN452430
发货至: 中国

Quick Overview for PPP2R4 抗体 (C-Term) (ABIN452430)

抗原

See all PPP2R4 抗体
PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

适用

  • 56
  • 27
  • 23
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 犬

宿主

  • 51
  • 7
  • 1
山羊

克隆类型

  • 47
  • 12
多克隆

标记

  • 38
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This PPP2R4 antibody is un-conjugated

应用范围

  • 35
  • 19
  • 15
  • 10
  • 8
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    c-GSLLPIHPVT SG

    特异性

    This antibody is expected to recognize all reported isoforms (NP_821068.1, NP_066954.2, NP_821070.1).

    交叉反应 (详细)

    Species reactivity (expected):Canine (Dog), Bovine.
    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography.

    免疫原

    Peptide with sequence from the C-Terminus of the protein sequence according to NP_821068.1, NP_066954.2, NP_821070.1. Genename: PPP2R4
  • 应用备注

    Peptide ELISA: 1/32000. Western Blot: Use at 0.5-2.0 μg/mL. Approx 37 kDa band observed in Human Liver lysates and in lysates of cell line HepG2(Calculated MW of 36.7 kDa according to NP_066954.2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris-saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

    别名

    PPP2R4 / PTPA

    背景

    Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.Synonyms: PP2A subunit B' PR53 isoform, Phosphotyrosyl phosphatase activator, Serine/threonine-protein phosphatase 2A regulatory subunit B'

    基因ID

    5524

    NCBI登录号

    NP_001180326

    UniProt

    Q15257

    途径

    PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades
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