PDGFRA 抗体 (Biotin)
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- 抗原 See all PDGFRA 抗体
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PDGFRA antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
- 交叉反应 (详细)
- Species reactivity (tested):Human
- 产品特性
- Synonyms: PDGF-R-alpha, PDGF Receptor alpha, Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A
- 免疫原
- CD140a-transfected NIH 3T3 cells
- 克隆位点
- 16A1
- 亚型
- IgG1
- Top Product
- Discover our top product PDGFRA Primary Antibody
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- 应用备注
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Indirect immunofluorescence analysis by Flow cytometry: 3 μg/mL as starting dilution.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- 别名
- CD140a / PDGFRA (PDGFRA 产品)
- 背景
- CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
- 基因ID
- 5156
- UniProt
- P16234
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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