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PDGFRA 抗体 (APC)

PDGFRA 适用: 人 FACS 宿主: 小鼠 Monoclonal 16A1 APC
产品编号 ABIN452286
发货至: 中国
  • 抗原 See all PDGFRA 抗体
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This PDGFRA antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This Mouse monoclonal antibody 16A1 recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
    产品特性
    Synonyms: PDGF-R-alpha, PDGF Receptor alpha, Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A
    纯化方法
    Size-Exclusion Chromatography
    免疫原
    CD140a-transfected NIH 3T3 cells
    克隆位点
    16A1
    亚型
    IgG1
    Top Product
    Discover our top product PDGFRA Primary Antibody
  • 应用备注
    Flow Cytometry: 10 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension. The content of a vial (0.25 ml) is sufficient for 25 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    别名
    CD140a / PDGFRA (PDGFRA 产品)
    别名
    AI115593 antibody, CD140a antibody, Pdgfr-2 antibody, APDGFR antibody, PDGFACE antibody, CD140A antibody, PDGFR-2 antibody, PDGFR2 antibody, RHEPDGFRA antibody, PDGFR antibody, PDGFR-A antibody, platelet derived growth factor receptor alpha antibody, platelet derived growth factor receptor, alpha polypeptide antibody, platelet-derived growth factor receptor, alpha polypeptide L homeolog antibody, platelet-derived growth factor receptor, alpha polypeptide antibody, PDGFRA antibody, Pdgfra antibody, pdgfra.L antibody
    背景
    CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
    基因ID
    5156
    UniProt
    P16234
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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