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- 抗原 See all PML 抗体
- PML (Promyelocytic Leukemia (PML))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PML antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody recognizes normal PML proteins of lower Molecular Weight, and also recognizes the High Molecular Weight PML/RAR-alpha Chimeric protein in promyelocytic leukemia patients.
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 产品特性
- Synonyms: RING finger protein 71, MYL, TRIM19, Probable transcription factor PML, Tripartitemotif-containing protein 19
- 纯化方法
- Affinity Chromatography on Protein G.
- 免疫原
- Recombinant partial Human PML.
- 克隆位点
- B3E9
- 亚型
- IgG1
- Top Product
- Discover our top product PML Primary Antibody
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anti-Promyelocytic Leukemia (PML) (AA 411-510) antibody
PML 适用: 人 WB, IF, ELISA, PLA 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Promyelocytic Leukemia (PML) (N-Term) antibodyPML 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 470-499), (Sumoylation Site) antibodyPML 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 300-600) antibodyPML 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (C-Term) antibodyPML 适用: 人, 小鼠, 大鼠, 马, Cow, 豚鼠, Pig, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 411-510) antibodyPML 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Promyelocytic Leukemia (PML) (AA 470-499), (Sumoylation Site) antibodyPML 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB2570 unconjugated
anti-Promyelocytic Leukemia (PML) (N-Term) antibodyPML 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 588-637) antibodyPML 适用: 人, 小鼠, 大鼠, 马, Cow, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Promyelocytic Leukemia (PML) (AA 59-239) antibodyPML 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: Use PML antibody at 1/2,000 dilution to differentiate normal PML andChimeric PML/RAR alpha molecules based on their molecular weight.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore by adding appropriate volume of distilled water to reach a final antibody concentration of 1.0 mg/mL.
- 缓冲液
- 0.01 M PBS, pH 7.4 without preservatives.
- 储存液
- Without preservative
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Store the antibody (in aliquots) at -20 °C. After reconstitution, aliquot and store at -20 °C.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- PML (Promyelocytic Leukemia (PML))
- 别名
- PML / RNF71 (PML 产品)
- 别名
- MYL antibody, PP8675 antibody, RNF71 antibody, TRIM19 antibody, 1200009E24Rik antibody, AI661194 antibody, Trim19 antibody, RGD1562602 antibody, PML antibody, promyelocytic leukemia antibody, PML antibody, Pml antibody
- 背景
- PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals.Synonyms: MYL, Probable transcription factor PML, RING finger protein 71, TRIM19, Tripartite motif-containing protein 19
- 基因ID
- 5371
- UniProt
- P29590
- 途径
- p53 Pathway, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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