Metabotropic Glutamate Receptor 6 抗体 (C-Term)
Quick Overview for Metabotropic Glutamate Receptor 6 抗体 (C-Term) (ABIN437971)
抗原
See all Metabotropic Glutamate Receptor 6 (GRM6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- affinity purified
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免疫原
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AAPPQNENAEDAK
Corresponding to the carboxyterminus of rat mGluR6 -
亚型
- IgG
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应用备注
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Suggested dilutions:
Western blot: 1:2000-1:3000
Immunohistochemistry: 1:300
Dilutions listed as a recommendation. Optimal dilution should be determined by investigator -
说明
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This antibody is useful for Western blot, where a band is seen at approx. 96 kDa. Neurons of expected brain regions stain well. Staining is not recommended for human or rat tissues
Note: A customer found a band in the 60-70 kDa range corresponding to the mGluR6 precursor. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1 % BSA, Tris-glycine with 0.1 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Aliquot as undiluted antisera and immediately place at -20°C.
Antisera may have become trapped in top of vial during shipping. Centrifugation of vial is recommended before opening.
Repeated freeze/thaw cycles compromise the integrity of the antiserum. -
储存条件
- -20 °C
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有效期
- 6 months
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- Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
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别名
- mGluR6
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背景
- Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
抗原
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