CD15 抗体 (APC)
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北京 101111
Quick Overview for CD15 抗体 (APC) (ABIN401770)
抗原
See all CD15 (FUT4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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无交叉反应
- 猪
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交叉反应 (详细)
- Species reactivity (tested):Human.
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亚型
- IgM
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 15 mM Sodium Azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))
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别名
- CD15
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背景
- CD15 (Lewis X, Le(x), stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.Synonyms: Lacto-N-Fucopentaose III, Lewis X, SSEA1, Stage-Specific Embryonic Antigen, X-Hapten
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UniProt
- P22083
抗原
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