CTNNA1 抗体 (pSer641)
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北京 101111
Quick Overview for CTNNA1 抗体 (pSer641) (ABIN401554)
抗原
See all CTNNA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer641
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特异性
- This antibody detects endogenous levels of Alpha-Catenin only when phosphorylated at Serine 641.
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纯化方法
- Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- Peptide sequence around the phosphorylation site of Serine 641 (D-D-Sp-D-F) derived from Human Alpha-Catenin.
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anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 637-906) antibody
CTNNA1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (C-Term) antibodyCTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) antibodyCTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 143-292) antibodyCTNNA1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (Internal Region) antibodyVerified CTNNA1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 371-574) antibodyCTNNA1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 8B6C1 unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 2-228) antibodyCTNNA1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 1-288) antibodyCTNNA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) (AA 152-250) antibodyCTNNA1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) antibodyCTNNA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500approx. 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at-20 °C.
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- CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
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别名
- Catenin alpha-1 / CTNNA1
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背景
- The distinct peripheral cytosolic proteins, alpha, beta and gamma-catenin (102, 94 and 86 kDa) found in many tissues bind to the conserved cytoplasmic tail domain of the cell-adhesion cadherins. Catenins link E-cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt-1 proto-oncogene. They are good candidates for mediating transduction of cell-cell contact positional signals to the cell interior. Absence of alpha-catenin is found in certain tumor cell lines and reduced levels in certain human carcinomas. Beta-catenin binds directly to the cytoplasmic tail of E-cadherin. It binds to the N-terminus of alpha-catenin and interacts with the protein product of the tumor suppressor gene APC. This interaction involves a 15-aa repeat in the APC. Beta-catenin cell levels seem to be controlled by APC. The central core region of beta-catenin is involved in mediation of cadherin-catenin complex interaction with EGFR.Synonyms: Alpha Catenin, Alpha E-catenin, Cadherin-associated protein, NY-REN-13 antigen
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基因ID
- 1495
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NCBI登录号
- NP_001894
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UniProt
- P35221
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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