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PRDM1 抗体 (C-Term)

The 兔 多克隆 anti-PRDM1 antibody is suitable to detect PRDM1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 EIA.
产品编号 ABIN401477
发货至: 中国
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Quick Overview for PRDM1 抗体 (C-Term) (ABIN401477)

抗原

See all PRDM1 抗体
PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

适用

  • 64
  • 20
  • 13
  • 4
  • 4
  • 3
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  • 2
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  • 1
  • 1
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人, 小鼠, 大鼠

宿主

  • 39
  • 26
  • 3
  • 1

克隆类型

  • 42
  • 27
多克隆

标记

  • 53
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This PRDM1 antibody is un-conjugated

应用范围

  • 53
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  • 14
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  • 2
  • 2
  • 1
  • 1
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody is directed against BLIMP1 protein.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide corresponding to a region near the C-terminus of human, mouse, and rat PRDM1/BLIMP1

    亚型

    IgG
  • 应用备注

    ELISA: 1/65,000 - 1/80,000. Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.15 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

    别名

    PRDM1 / BLIMP1

    背景

    PRDM1/Blimp1 (PR domain zinc finger protein 1, PR domain-containing protein 1, Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Positive regulatory domain I-binding factor 1, PRDIbinding factor 1, or PRDI-BF1, or Betalymphocyte-induced maturation protein 1) is one of several transcription factors which drives the maturation of B-lymphocytes into Ig secreting cells. In the nucleus, PRDM1/BLIMP1 functions as a transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Transcription of the PRDM1 gene is increased upon virus induction. PRDM1/Blimp1 also interacts with PRMT5. Two alternatively spliced transcript variants that encode different isoforms have been reported.Synonyms: BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain zinc finger protein 1, PR domain-containing protein 1, PRDI-BF1, PRDI-binding factor 1, Positive regulatory domain I-binding factor 1

    基因ID

    639

    NCBI登录号

    NP_001189

    UniProt

    O75626

    途径

    Regulation of Muscle Cell Differentiation
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